Fenbendazole is a drug that has been found to have the ability of killing cancer cells. The effectiveness of fenbendazole use with vitamin E for cancer treatment, however, is based on positive reviews from individuals who took part in clinical trials and studies performed by medical professionals and scientists. However, in 2011, there is proof that the combination is also effective in treating prostate cancer both in a living body and clinical trials.
The proof of the synergistic combination of vitamin E and Fenbendazole was discovered in 2011 Combining vitamin E as well as other vitamins with fenbendazole can improve its effectiveness. Combining with high doses of retinol, vitamin b2, vitamin b1, vitamin k3, cholecalciferol, bioavailable niacin, folate, vitamin d3, vitamin A, biotin, and pantothenic acid can improve the effectiveness of fenbendazole against lymphoma in mice to between 1 ½ to 2 times. See fig 6 for certain vitamin formulation ingredients.
Scientists are still conducting more research to determine the effectiveness of these treatments, but the anti-tumor effect of fenbendazole can also be synergetically improved through vitamin b1 as well as other vitamin groups. We suggest that vitamin b6, b1, b9, and vitamin d are combined with a treatment routine containing fenbendazole or other benzimidazole medications. Another excellent example of medications combined (biotherapy), in which one of the medications is similar to fenbendazole is combining temozolomide for glioblastoma and mebendazole (an anthelmintic benzimidazole). Two months’ daily dose of 15mg/kg of temozolomide and 50mg/kg of mebendazole can improve the human’s survival benefit to up to 72.4% as opposed to about 41.4% survival rate when using only temozolomide.
Medical experts recommend that fenbendazole powder should be used in addition to other agents. The combinations of fenbendazole with other medications are possible because it’s a selective chemical which can kill tumor cells in the way that standard antibiotics such as aminoglycoside.
Several pieces of evidence are available that indicate that the use of chemotherapy agents which disrupts microtubule at metronomic or low doses like taxanes and vinca alkaloids can cause a positive immunomodulatory activity on an organism that might be responsible for eliminating cancer’s immunosuppressive effect.
Very soon, mebendazole will not only be regarded as a repackaged medication but a part of the metronomic chemotherapy strategy. Fenbendazole might probably be on the same level if it was not a veterinary medication.
At the same time, fenbendazole or any other type of anthelmintic drug can be used in combination with a high dose of retinoid, vitamin E, vitamin C, and other vitamins that can demonstrate strong anti-tumor effect against certain types of cancer. This high dose of retinoid and some other vitamins will also have a potentiating effect on the treatment’s effectiveness of fenbendazole against cancers.
It is obvious that anthelmintic drug use has a dual role in cancer therapy. Fenbendazole might be used in combination with high doses of vitamin E, beta-carotene, selenium and other substances to improve the effectiveness of fenbendazole as well as the treatment’s other side effects.